Search Result

Pathways Recommended:	MAPK/ERK Pathway

Results for "

MAPK Kinase Kinase Kinase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	MAP4K (1) MAPKAPK2 (MK2) (2) p38 MAPK (18) AAK1 (2) Anaplastic lymphoma kinase (ALK) (1) Apoptosis (5) Aurora Kinase (1) Autophagy (4) Bcr-Abl (1) CaMK (1) Casein Kinase (3) CDK (4) COX (1) Cyclin G-associated Kinase (GAK) (2) DYRK (1) EGFR (2) ERK (11) Ferroptosis (2) FGFR (1) FLT3 (1) HSP (1) Interleukin Related (1) JNK (1) LIM Kinase (LIMK) (3) MEK (2) NF-κB (5) PDGFR (1) Phosphatase (1) Phosphodiesterase (PDE) (1) Pim (1) PROTACs (4) Raf (2) Reactive Oxygen Species (1) RET (1) Salt-inducible Kinase (SIK) (3) SHP2 (1) Src (3) TNF Receptor (1) ULK (2) Wee1 (2) Wnt (1)
By Research Areas:	Cancer (25) Cardiovascular Disease (1) Inflammation/Immunology (18) Metabolic Disease (2) Neurological Disease (3)

By Targets:

MAP4K (1)

MAPKAPK2 (MK2) (2)

p38 MAPK (18)

AAK1 (2)

Anaplastic lymphoma kinase (ALK) (1)

Apoptosis (5)

Aurora Kinase (1)

Autophagy (4)

Bcr-Abl (1)

CaMK (1)

Casein Kinase (3)

CDK (4)

COX (1)

Cyclin G-associated Kinase (GAK) (2)

DYRK (1)

EGFR (2)

ERK (11)

Ferroptosis (2)

FGFR (1)

FLT3 (1)

HSP (1)

Interleukin Related (1)

JNK (1)

LIM Kinase (LIMK) (3)

MEK (2)

NF-κB (5)

PDGFR (1)

Phosphatase (1)

Phosphodiesterase (PDE) (1)

Pim (1)

PROTACs (4)

Raf (2)

Reactive Oxygen Species (1)

RET (1)

Salt-inducible Kinase (SIK) (3)

SHP2 (1)

Src (3)

TNF Receptor (1)

ULK (2)

Wee1 (2)

Wnt (1)

By Research Areas:

Cancer (25)

Cardiovascular Disease (1)

Inflammation/Immunology (18)

Metabolic Disease (2)

Neurological Disease (3)

Inhibitors & Agonists

Screening Libraries

Peptides

Natural
Products

Recombinant Proteins

Antibodies

Targets Recommended: p38 MAPK MAP4K MNK MAPKAPK2 (MK2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P3031

Mitogen-activated protein kinase 1 MAPK1	p38 MAPK NF-κB	Inflammation/Immunology
Mitogen-activated protein kinase 1 (MAPK1) can activate the downstream p38/NF-κB pathway. Mitogen-activated protein kinase 1 can regulate cellular processes in various sepsis-associated diseases. MAPK-catalyzed phosphorylation of substrate proteins functions as a switch to turn on or off the activity of the substrate protein .

HY-142452

Pan-RAF kinase inhibitor 1	Raf	Cancer
Pan-RAF kinase inhibitor 1 is a potent inhibitor of Pan-RAF kinase. Pan-RAF kinase inhibitor 1 regulates MAPK signaling by inhibiting RAF kinase, thereby exerting an effect on the proliferation of RAS-mutant tumor cells. Pan-RAF kinase inhibitor 1 has the potential for the research of cancer diseases (extracted from patent WO2021110141A1, compound 16B) .

HY-107620

PD 198306	MEK	Neurological Disease
PD 198306 is a selective MAPK/ERK-kinase (MEK) inhibitor. PD 198306 results in an observable reduction in the Streptozocin induced increase in the level of active ERK1 and 2. Antihyperalgesic effects .

HY-15496

E6201 ER-806201	MEK FLT3	Cancer
E6201 (ER-806201) is an ATP-competitive dual kinase inhibitor of MEK1 and FLT3. E6201 inhibits MEK1- induced ERK2 phosphorylation with an IC₅₀ value of 5.2 nM, MKK4-induced JNK phosphorylation with an IC₅₀ value of 91 nM, and MKK6-induced p38 MAPK phosphorylation with an IC₅₀ value of 19 nM. Anti-tumor and anti-psoriasis efficacy .

HY-U00324

p38 MAPK-IN-2

p38 MAPK Autophagy Cancer

p38 MAPK-IN-2 is an inhibitor of p38 kinase.

p38 MAPK-IN-2	p38 MAPK Autophagy	Cancer
p38 MAPK-IN-2 is an inhibitor of p38 kinase.

HY-152087

DCZ19931	ERK p38 MAPK	Cardiovascular Disease
DCZ19931 is a potent multi-targeting kinase inhibitor. DCZ19931 has anti-angiogenic effects on ocular neovascularization. DCZ19931 also inhibits ERK1/2-MAPK and p38-MAPK signaling .

HY-120595

JNJ-49095397 RV568	p38 MAPK Src	Inflammation/Immunology
JNJ-49095397 (RV568) is an inhaled narrow-spectrum kinase inhibitor (NSKI) against both the α and γ isoforms of p38 MAPK. JNJ-49095397 also inhibits SRC kinase family, specifically haematopoietic kinase (HCK) JNJ-49095397 shows potent anti-inflammatory effects and can be used for the research of chronic obstructive pulmonary disease (COPD) and asthma .

HY-112181

KO-947

3 Publications Verification

ERK Cancer

KO-947 is a potent and selective inhibitor of ERK1/2 kinases with potential utility in MAPK pathway dysregulated tumors.
HY-49073

p38 MAP Kinase Inhibitor Ⅵ

p38 MAPK Cancer

p38 MAP Kinase Inhibitor VI (compound c32) is a p38 MAPK inhibitor with an inhibition rate of 24% .
HY-161293

p38-α MAPK-IN-6

p38 MAPK Cancer

p38-α MAPK-IN-6 (compound 3a) is a p38α mitogen-activated protein kinase inhibitor .

KO-947 3 Publications Verification	ERK	Cancer
KO-947 is a potent and selective inhibitor of ERK1/2 kinases with potential utility in MAPK pathway dysregulated tumors.

p38 MAP Kinase Inhibitor Ⅵ	p38 MAPK	Cancer
p38 MAP Kinase Inhibitor VI (compound c32) is a p38 MAPK inhibitor with an inhibition rate of 24% .

p38-α MAPK-IN-6	p38 MAPK	Cancer
p38-α MAPK-IN-6 (compound 3a) is a p38α mitogen-activated protein kinase inhibitor .

HY-145026

ERK1/2 inhibitor 4	ERK	Inflammation/Immunology Cancer
ERK1/2 inhibitor 5 is a potent inhibitor of ERK1/2. Mitogen-activated protein kinase (MAPK) plays an extremely important role in the signal transduction pathway, and extracellular signal regulated kinase (ERK) is a member of the MAPK family. ERK1/2 inhibitor 5 has the potential for the research or prevention of cancer, inflammation or other proliferative diseases (extracted from patent WO2020238776A1) .

HY-145027

ERK1/2 inhibitor 5	ERK	Cancer
ERK1/2 inhibitor 5 is a potent inhibitor of ERK1/2. Mitogen-activated protein kinase (MAPK) plays an extremely important role in the signal transduction pathway, and extracellular signal regulated kinase (ERK) is a member of the MAPK family. ERK1/2 inhibitor 5 has the potential for the research or prevention of cancer, inflammation or other proliferative diseases (extracted from patent WO2020238776A1) .

HY-145025

ERK1/2 inhibitor 3	ERK	Inflammation/Immunology Cancer
ERK1/2 inhibitor 3 is a potent inhibitor of ERK1/2. Mitogen-activated protein kinase (MAPK) plays an extremely important role in the signal transduction pathway, and extracellular signal regulated kinase (ERK) is a member of the MAPK family. ERK1/2 inhibitor 3 has the potential for the research or prevention of cancer, inflammation or other proliferative diseases (extracted from patent WO2021218912A1, compound 1) .

HY-145028

ERK1/2 inhibitor 6	ERK	Inflammation/Immunology Cancer
ERK1/2 inhibitor 6 is a potent inhibitor of ERK1/2. Mitogen-activated protein kinase (MAPK) plays an extremely important role in the signal transduction pathway, and extracellular signal regulated kinase (ERK) is a member of the MAPK family. ERK1/2 inhibitor 6 has the potential for the research or prevention of cancer, inflammation or other proliferative diseases (extracted from patent WO2021063335A1, compound 1) .

HY-112389

p38 MAP Kinase Inhibitor III 1 Publications Verification	p38 MAPK	Inflammation/Immunology
p38 MAP Kinase Inhibitor III (compound 7h) is a p38 MAPK inhibitor with an ₅₀ of 0.9 μM. p38 MAP Kinase Inhibitor III also inhibits IL-1β and TNF-α release with ₅₀ values of 0.37 μM and 0.044 μM, respectively .

HY-112401

p38 MAP Kinase Inhibitor IV	p38 MAPK	Inflammation/Immunology
p38 MAP Kinase Inhibitor IV is a highly specific ATP-competitive p38α MAPK inhibitor with IC₅₀s of 0.13 and 0.55 μM for p38α and p38β MAPK, respectively .

HY-N1966

(E)-Osmundacetone 2 Publications Verification
(E)-Osmundacetone is the isomer of Osmundacetone. Osmundacetone significantly suppresses the phosphorylation of MAPKs, including JNK, ERK, and p38 kinases. Osmundacetone has a neuroprotective effect against oxidative stress .

HY-12072

Lck Inhibitor 1 Publications Verification	Src	Inflammation/Immunology
Lck Inhibitor is a potent, orally active Lck (lymphocyte specific kinase) inhibitor with IC₅₀s of 7, 2.1, 4.2 and 200 nM for Lck, Lyn, Src and Syk kinases, respectively. Lck Inhibitor shows >1000-fold selectivity for Lck over MAPK, CDK and RSK family representatives. Lck Inhibitor inhibits T cell proliferation and in vivo models of arthritis .

HY-110193

SPP-86 1 Publications Verification	RET	Cancer
SPP-86 is a potent and selective cell permeable inhibitor of RET tyrosine kinase, with an IC₅₀ of 8 nM. SPP-86 inhibits RET-induced phosphatidylinositide 3-kinases (PI3K)/Akt and MAPK signaling, also inhibits RET-induced estrogen receptorα (ERα) phosphorylation in MCF7 cells . SPP-86 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-148063

DB0614	PROTACs AAK1 Aurora Kinase CaMK CDK Ferroptosis Salt-inducible Kinase (SIK) ULK Wee1 LIM Kinase (LIMK)	Others
DB0614 (Example 21) is a bifunctional compound targeted protein degradation of kinases. DB0614 degrades AAK1, AURKA, BMP2K, CAMKK1, CDK16, CML, CDK6, EIF2AK2, FER, GAK, LCK, LIMK2, MAP3KH, MAPK8, MAPK9, NEK9, PLK4, PTK2B, SIK2, STK17A, STK17B, ULK1, ULK3, and WEE1. DB0614 can be used for research of disease or disorder mediated by aberrant kinase activity .

HY-148061

DB1113	PROTACs Bcr-Abl CDK Salt-inducible Kinase (SIK) Cyclin G-associated Kinase (GAK) MAP4K MAPKAPK2 (MK2) Ferroptosis ULK LIM Kinase (LIMK)	Others
DB1113 (Example 24) is a bifunctional compound targeted protein degradation of kinases. DB1113 degrades ABL1, ABL2, BLK, CDK11B, CDK4, CSK, EPHA3, FER, GAK, LIMK1, MAP3K20, MAP4K1, MAP4K2, MAP4K3, MAP4K5, MAPK14, MAPK7, MAPK8, MAPK9, MAPKAPK2, MAPKAPK3, NLK, PDIK1L, PTK2B, RIPK1, RPS6KA1, RPS6KA3, SIK2, SIK3, STK35, TNK2, and ULK1. DB1113 can be used for research of disease or disorder mediated by aberrant kinase activity .

HY-N4126

6-Demethoxytangeretin	Anaplastic lymphoma kinase (ALK)	Neurological Disease Inflammation/Immunology Cancer
6-Demethoxytangeretin is a citrus flavonoid isolated from Citrus reticulata. 6-Demethoxytangeretin exerts anti-inflammatory activity and anti-allergic activity, suppresses production and gene expression of interleukin-6 in human mast cell-1 via anaplastic lymphoma kinase (ALK) and mitogen-activated protein kinase (MAPK) pathways . 6-Demethoxytangeretin facilitates the CRE-mediated transcription associated with learning and memory in cultured hippocampal neurons .

HY-160765

WNTinib APS-8-100-2	Wnt Apoptosis	Cancer
WNTinib (APS-8-100-2) is a multi-kinase inhibitor that selectively antagonizes β-catenin (CTNNB1) mutated hepatocellular carcinoma (HCC). WNTinib downregulates oncogenicWntsignaling by inhibiting KIT/MAPK and downstream EZH2 activation .

HY-136990

GLPG0259	Others	Cancer
GLPG0259 is a ATP-competitive inhibitor of MAPK-activated protein kinase 5 (MK5) with oral activity. GLPG0259 reduces inflammation and bone destruction in a mouse model of collagen-induced arthritis. GLPG0259 also inhibited the metastasis of prostate cancer (PCa) cells .

HY-112345

PD-089828	FGFR PDGFR EGFR Src	Cancer
PD-089828 is an ATP competitive inhibitor of FGFR-1, PDGFR-β and EGFR (IC₅₀s=0.15, 1.76, and 5.47 µM, respectively) and a noncompetitive inhibitor of c-Src tyrosine kinase (IC₅₀=0.18 µM). PD-089828 also inhibits *MAPK* with an IC₅₀ of 7.1 µM. PD-089828 inhibits PDGF-, EGF- and bFGF-mediated tyrosine kinase receptor autophosphorylation in vitro. PD-089828 has a long-lasting cellular activity .

HY-111820

CK1-IN-1	Casein Kinase	Inflammation/Immunology
CK1-IN-1 is a *casein kinase* 1 (CK1) inhibitor extracted from patent WO2015119579A1, compound 1c, has IC₅₀*s of 15 nM, 16 nM, 73 nM for CK1δ, and CK1ε, p38σ MAPK*, respectively .

HY-P10072A

MK2-IN-5 acetate Hsp25 Kinase inhibitor acetate; Mk2 pseudosubstrate acetate	JNK HSP MAPKAPK2 (MK2) p38 MAPK ERK	Others
MK2-IN-5 (Hsp25 kinase inhibitor) acetate is a Mk2 pseudosubstrate (K_i= 8 μM). MK2-IN-5 acetate targets the protein interaction domain in the MAPK pathway. MK2-IN-5 acetate inhibits HSP25 and HSP27 phosphorylation .

HY-N6959

Osmundacetone	Reactive Oxygen Species Apoptosis	Metabolic Disease
Osmundacetone is a natural product isolated from Osmundae Rhizoma, with neuroprotective and anti-apoptotic effects. Osmundacetone also has DPPH scavenging activity and anti-oxidative stress activity. Osmundacetone inhibits MAPK phosphorylation, including JNK, ERK, and p38 kinase. Osmundacetone can be a potential agent for the research of neurodegenerative diseases .

HY-148062

RSS0680	PROTACs CDK AAK1 Cyclin G-associated Kinase (GAK) Salt-inducible Kinase (SIK) LIM Kinase (LIMK) Wee1	Others
RSS0680 (Example 22) is a bifunctional compound targeted protein degradation of kinases. RSS0680 degrades AAK1, CDK1, CDK16, CDK2, CDK4, CDK6, EIF2AK4, GAK, LATSl, LIMK2, MAPK6, MAPKAPK5, MARK2, MARK4, MKNK2, NEK9, RPS6KB1, SIK2, SNRK, STK17A, STK17B, STK35, and WEEl. RSS0680 can be used for research of disease or disorder mediated by aberrant kinase activity .

HY-10406

Talmapimod 3 Publications Verification SCIO-469	p38 MAPK	Cancer
Talmapimod (SCIO-469) is an orally active, selective, and ATP-competitive p38α inhibitor with an IC₅₀ of 9 nM. Talmapimod shows about 10-fold selectivity over p38β, and at least 2000-fold selectivity over a panel of 20 other kinases, including other MAPKs .

HY-10406A

Talmapimod hydrochloride SCIO-469 hydrochloride	p38 MAPK	Cancer
Talmapimod (SCIO-469) hydrochloride is an orally active, selective, and ATP-competitive p38α inhibitor with an IC₅₀ of 9 nM. Talmapimod hydrochloride shows about 10-fold selectivity over p38β, and at least 2000-fold selectivity over a panel of 20 other kinases, including other MAPKs .

HY-135906

CK2/ERK8-IN-1	Casein Kinase ERK Pim DYRK Apoptosis	Cancer
CK2/ERK8-IN-1 is a dual *casein kinase* 2 (CK2) (K_i of 0.25 µM) and ERK8** (MAPK15, ERK7) inhibitor with IC₅₀s of 0.50 μM. CK2/ERK8-IN-1 also binds to PIM1, HIPK2 (*homeodomain-interacting protein kinase* 2), and DYRK1A with K_is of 8.65 µM, 15.25 µM, and 11.9 µM, respectively. CK2/ERK8-IN-1 has pro-apoptotic** efficacy .

HY-N6246

Asperulosidic Acid	NF-κB ERK	Inflammation/Immunology Cancer
Asperulosidic Acid (ASPA), a bioactive iridoid glycoside, is extracted from the herbs of Hedyotis diffusa Willd. Asperulosidic Acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities . ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-activated protein kinase (MAPK) signaling pathways .

HY-137092

IACS-13909 1 Publications Verification	SHP2 Phosphatase	Cancer
IACS-13909 is a selective, potent and orally active SHP2 allosteric inhibitor with an IC₅₀ of 15.7 nM and a K_d of 32 nM. IACS-13909 is more selective for SHP2 than other phosphatases (including SHP1). IACS-13909 has antitumor activities and suppresses MAPK pathway signaling in receptor tyrosine kinases (RTK)-dependent cancers .

HY-108645

AL 8697	p38 MAPK Autophagy	Inflammation/Immunology
AL 8697 is a specific and orally active p38α MAPK inhibitor with an IC₅₀ of 6 nM. AL 8697 displays 14-fold greater inhibition of p38α compared to p38β (IC₅₀=82 nM), and 300-fold selectivity for p38α over a panel of 91 kinases. Anti-inflammatory activity .

HY-116035

Nimbolide 1 Publications Verification	NF-κB CDK Apoptosis	Cancer
Nimbolide is a triterpene compound that can be isolated from neem (Azadirachta indica), possesses anticancer and antiproliferative activity. Nimbolide induces tumor cell apoptosis by inhibiting NF-κB and CDK4/CDK6 kinase. Nimbolide suppresses the Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways .

HY-N1818

Deoxysappanone B 3-Deoxysappanone B	p38 MAPK	Neurological Disease Inflammation/Immunology
Deoxysappanone B (3-Deoxysappanone B) is a homoisoflavone compound isolated from Caesalpinia sappan L (Lignum Sappan). Deoxysappanone B has anti-neuroinflammatory and neuroprotective effects and inhibits the production of neuroinflammatory mediators by blocking the IκB kinase (IKK)-NF-κB and p38/ERK MAPK pathways. Deoxysappanone B can be used in disease studies of neuritis and inflammation-related neurological damage .

HY-W015445

SD-169	p38 MAPK	Metabolic Disease
SD-169 is an orally active ATP-competitive inhibitor of p38α MAPK, with an IC₅₀ of 3.2 nM. SD-169 also weakly inhibits p38β MAPK with an IC₅₀ of 122 nM. SD-169 prevents the development and progression of diabetes by inhibiting T cell infiltration and activation .

HY-131335

p38α inhibitor 2	p38 MAPK	Inflammation/Immunology
p38α inhibitor 2 is a highly potent and selective p38α MAPK inhibitor, with a pIC₅₀ of 9.6. p38α inhibitor 2 inhibits the hERG ion channel (IC₅₀=27 μM) and shows a promising selectivity profile when tested in a panel of 51 other protein kinases (<30% inhibition at 10 μM concentration) and a panel of 141 other biological targets .

HY-10456

TAK-715 10+ Cited Publications	p38 MAPK Casein Kinase	Inflammation/Immunology
TAK-715 is an orally active and potent p38 MAPK inhibitor with IC₅₀s of 7.1 nM, 200 nM for p38α and p38β, respectively. TAK-715 inhibits *casein kinase* I (CK1δ/ε)** to regulate activation of Wnt/β-catenin signaling. TAK-715 shows good significant efficacy in a rat arthritis model .

HY-16558

Butein 3 Publications Verification 2’,3,4,4’-tetrahydroxy Chalcone	EGFR Autophagy Apoptosis Phosphodiesterase (PDE)	Cancer
Butein is a cAMP-specific PDE inhibitor with an IC₅₀ of 10.4 μM for PDE4 . Butein is a specific protein tyrosine kinase inhibitor with IC₅₀s of 16 and 65 μM for EGFR and p60 ^c-src in HepG2 cells . Butein sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a . Butein is a SIRT1 activator (STAC).

HY-148552

Anti-inflammatory agent 35	p38 MAPK ERK NF-κB Interleukin Related TNF Receptor	Inflammation/Immunology
Anti-inflammatory agent 35 (compound 5a27) is an orally active curcumin analogue with anti-inflammatory activity. Anti-inflammatory agent 35 blocks mitogen-activated protein kinase (MAPK) signaling and p65 nuclear translocation of NF-kB. Anti-inflammatory agent 35 also inhibits yellow neutrophil infiltration and pro-inflammatory cytokine production. Anti-inflammatory agent 35 significantly attenuates lipopolysaccharide (LPS)-induced acute lung injury (ALI) in vivo .

HY-150605

ERK5-IN-3	ERK	Cancer
ERK5-IN-3 (compound 33j) is a potent and selective ERK5 (extracellular signal-related kinase 5) inhibitor, with an IC₅₀ of 6 nM. ERK5-IN-3 shows antiproliferation activity against Hela cells, with an IC₅₀ of 31 nM .

HY-10320

Doramapimod Maximum Cited Publications 23 Publications Verification BIRB 796	p38 MAPK Raf Autophagy	Inflammation/Immunology Cancer
Doramapimod (BIRB 796) is an orally active, highly potent p38 MAPK inhibitor, which has an IC₅₀ for p38α=38 nM, for p38β=65 nM, for p38γ=200 nM, and for p38δ=520 nM. Doramapimod has picomolar affinity for p38 kinase (K_d=0.1 nM). Doramapimod also inhibits B-Raf with an IC₅₀ of 83 nM .

HY-N0632

Esculentoside A 2 Publications Verification	COX NF-κB	Inflammation/Immunology
Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta . Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models , has selective inhibitory activity towards cyclooxygenase-2 (COX-2) . Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways .

HY-148065

FMF-06-098-1	PROTACs	Cancer
FMF-06-098-1 is a multitargeted depressant. FMF-06-098-1 can be used to target degradation kinases which degrades AAK1, AΒL2, AURKA, AURKB, BUBIB, CDC7, CDK1, CDK12, CDK13, CDK2, CDK4, CDk6, CDK7, CDK9, CHEK1, CSNKID, EPHA1, PER, FGFR1, GAK, IRAK4, ITK, LIMK2, MAP4K2, MAP4K3, MAPK6, MAPK7, MARK4, MELK, PKN3, PLK4, PRKAA1, PTK2, PTK6, RPS6KA4, S1K2, STK35, TNK2, UHMK1, ULK1, and WEE1 .

Cat. No.	Product Name

HY-L164

Serine/Threonine Kinase Inhibitor Library

1267 Compounds compounds

Protein serine/threonine kinases (PSKs) are protein kinases that use ATP as a high-energy donor molecule to transfer phosphate groups to serine/threonine residues of target protein. As an important signal transduction regulator, serine/threonine kinases can affect the function of target proteins by disrupting enzyme activity or binding of target proteins to other proteins. Serine/threonine kinases are involved in the regulation of immune response, cell proliferation, differentiation, apoptosis and other physiological processes. Serine/threonine kinase inhibitors are an important class of compounds that have been widely studied in cancer, chronic inflammation, autoimmune diseases, aging and other diseases.

MCE designs a unique collection of 1267 serine/threonine kinase inhibitors, mainly targeting the receptor PKA, Akt, PKC, MAPK/ERK, etc, which is an effective tool for development and research of anti-cancer, anti-chronic inflammatory diseases, anti-autoimmune diseases and anti-aging compounds.

HY-L010

MAPK Compound Library

510 compounds

MAPK families play an important role in complex cellular programs like proliferation, differentiation, development, transformation, and apoptosis. In mammalian cells, four MAPK families have been clearly characterized: ERK1/2, C-Jun N-terminal kinse/stress-activated protein kinase (JNK/SAPK) , p38 kinase and ERK5. They respond to different signals. Each MAPK-related cascade consists of three enzymes that are activated in series: a MAPK kinase kinase (MAPKKK), a MAPK kinase (MAPKK) and a MAP kinase (MAPK). MAPK signaling pathways has been implicated in the development of many human diseases including Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS) and various types of cancers.

MCE designs a unique collection of 510 MAPK signaling pathway inhibitors that act as a useful tool for MAPK-related drug screening and disease research.

Species:	Human (36) Mouse (3)
Tag:	His (20) Tag Free (11) GST (13) Flag (1)
Source:	Sf9 insect cells (2) Sf9 insect cells (19) P. pastoris (1) E. coli (17)

Cat. No.	Compare	Product Name	Species	Source

HY-P701803

	MAPK4 Protein, Human (Sf9, His, GST) MAPK4; Mitogen-activated protein Kinase 4; MAP Kinase 4; MAPK 4; Extracellular signal-regulated Kinase 4; ERK-4; MAP Kinase isoform p63; p63-MAPK	Human	Sf9 insect cells
	MAPK4, an atypical MAPK protein, phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5, forming a complex with intricate phosphorylation events. Interaction with MAPKAPK5 leads to ERK3/MAPK6 phosphorylation at Ser-189, activating MAPKAPK5, which reciprocally phosphorylates ERK3/MAPK6. The specific cellular role of this interplay, while unclear, suggests ERK3's potential involvement in promoting entry into the cell cycle. MAPK4 Protein, Human (Sf9, His, GST) is the recombinant human-derived MAPK4 protein, expressed by Sf9 insect cells , with N-8*His, N-GST labeled tag. The total length of MAPK4 Protein, Human (Sf9, His, GST) is 586 a.a., .

HY-P701679

	ERK3 Protein, Human MAPK6; Mitogen-activated protein Kinase 6; MAP Kinase 6; MAPK 6; Extracellular signal-regulated Kinase 3; ERK-3; MAP Kinase isoform p97; p97-MAPK	Human	E. coli
	ERK3 Protein, an atypical MAPK, phosphorylates MAP2 and MAPKAPK5. Interacting with MAPKAPK5, ERK3/MAPK6 undergoes Ser-189 phosphorylation, facilitating MAPKAPK5 activation. Activated MAPKAPK5 reciprocally phosphorylates ERK3/MAPK6. The complex's precise functional implications, especially in cell cycle entry, remain elusive. ERK3 Protein, Human is the recombinant human-derived ERK3 protein, expressed by E. coli , with tag free. The total length of ERK3 Protein, Human is 319 a.a., .

HY-P701680

	ERK3 Protein, Human (His) MAPK6; Mitogen-activated protein Kinase 6; MAP Kinase 6; MAPK 6; Extracellular signal-regulated Kinase 3; ERK-3; MAP Kinase isoform p97; p97-MAPK	Human	E. coli
	ERK3 Protein, an atypical MAPK, phosphorylates MAP2 and MAPKAPK5. Interacting with MAPKAPK5, ERK3/MAPK6 undergoes Ser-189 phosphorylation, facilitating MAPKAPK5 activation. Activated MAPKAPK5 reciprocally phosphorylates ERK3/MAPK6. The complex's precise functional implications, especially in cell cycle entry, remain elusive. ERK3 Protein, Human (His) is the recombinant human-derived ERK3 protein, expressed by E. coli , with N-6*His labeled tag. The total length of ERK3 Protein, Human (His) is 319 a.a., .

HY-P702735

	MAPK1 Protein, Human (Flag, His) MAPK1; mitogen-activated protein Kinase 1; PRKM1, PRKM2; ERK; ERK2; MAPK2; p41MAPK; ERK-2; MAPK 2; p42-MAPK; MAP Kinase 1; MAP Kinase 2; MAP Kinase isoform p42; protein tyrosine Kinase ERK2; mitogen-activated protein Kinase 2; extracellular signal-regulated Kinase 2; p38; p40; p41; ERT1; PRKM1; PRKM2; P42MAPK	Human	E. coli

HY-P701678

	ERK1 Protein, Human (GST) MAPK3; Mitogen-activated protein Kinase 3; MAP Kinase 3; MAPK 3; ERT2; Extracellular signal-regulated Kinase 1; ERK-1; Insulin-stimulated MAP2 Kinase; MAP Kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 Kinase; p44-ERK1	Human	E. coli
	ERK1 protein is an important serine/threonine kinase in the MAP kinase pathway and cooperates with MAPK1/ERK2 to activate the MAPK/ERK cascade. Stimulated by KIT and KITLG/SCF, this pathway plays a key role in cell growth, adhesion, survival, and differentiation. ERK1 Protein, Human (GST) is the recombinant human-derived ERK1 protein, expressed by E. coli , with N-GST labeled tag. The total length of ERK1 Protein, Human (GST) is 378 a.a., .

HY-P701801

	MAP4K6 Protein, Human (Sf9, GST) MINK1; Misshapen-like Kinase 1; GCK family Kinase MiNK; MAPK/ERK Kinase Kinase Kinase 6; MEK Kinase Kinase 6; MEKKK 6; Misshapen/NIK-related Kinase; Mitogen-activated protein Kinase Kinase Kinase Kinase 6	Human	Sf9 insect cells
	MAP4K6 protein is a key serine/threonine kinase that negatively regulates Ras-related Rap2-mediated signaling, affecting neuronal structure and AMPA receptor trafficking. Its importance is underlined by its important role in regulating synaptic density, dendritic complexity, and surface AMPA receptor expression in hippocampal neurons. MAP4K6 Protein, Human (Sf9, GST) is the recombinant human-derived MAP4K6 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of MAP4K6 Protein, Human (Sf9, GST) is 314 a.a., .

HY-P701790

	JNK3 Protein, Human MAPK10; Mitogen-activated protein Kinase 10; MAP Kinase 10; MAPK 10; MAP Kinase p49 3F12; Stress-activated protein Kinase 1b; SAPK1b; Stress-activated protein Kinase JNK3; c-Jun N-terminal Kinase 3	Human	E. coli
	JNK3 is a critical serine/threonine protein kinase in neuronal processes, regulating proliferation, differentiation, migration, and apoptosis. Activation through MAP2K4/MKK4 and MAP2K7/MKK7 leads to phosphorylation of JNK3, which in turn phosphorylates AP-1 components such as JUN and ATF2, thereby regulating AP-1 transcriptional activity. JNK3 Protein, Human is the recombinant human-derived JNK3 protein, expressed by E. coli , with tag free. The total length of JNK3 Protein, Human is 423 a.a., .

HY-P701791

	JNK3 Protein, Human (His) MAPK10; Mitogen-activated protein Kinase 10; MAP Kinase 10; MAPK 10; MAP Kinase p49 3F12; Stress-activated protein Kinase 1b; SAPK1b; Stress-activated protein Kinase JNK3; c-Jun N-terminal Kinase 3	Human	E. coli
	JNK3 is a critical serine/threonine protein kinase in neuronal processes, regulating proliferation, differentiation, migration, and apoptosis. Activation through MAP2K4/MKK4 and MAP2K7/MKK7 leads to phosphorylation of JNK3, which in turn phosphorylates AP-1 components such as JUN and ATF2, thereby regulating AP-1 transcriptional activity. JNK3 Protein, Human (His) is the recombinant human-derived JNK3 protein, expressed by E. coli , with N-6*His labeled tag. The total length of JNK3 Protein, Human (His) is 423 a.a., .

HY-P701814

	MKNK2 Protein, Human MKNK2; MAP Kinase-interacting serine/threonine-protein Kinase 2; MAP Kinase signal-integrating Kinase 2; MAPK signal-integrating Kinase 2; Mnk2	Human	E. coli
	MKNK2 is a serine/threonine protein kinase that centrally affects cellular processes by phosphorylating SFPQ/PSF, HNRNPA1, and EIF4E. MKNK2 sits at the intersection of environmental stress and cytokine signaling and regulates translation by enhancing the affinity of EIF4E for the mRNA cap, thereby affecting the translation machinery. MKNK2 Protein, Human is the recombinant human-derived MKNK2 protein, expressed by E. coli , with tag free. The total length of MKNK2 Protein, Human is 314 a.a., .

HY-P701705

	ASK1 Protein, Human (His) MAP3K5; Mitogen-activated protein Kinase Kinase Kinase 5; Apoptosis signal-regulating Kinase 1; ASK-1; MAPK/ERK Kinase Kinase 5; MEK Kinase 5; MEKK 5	Human	E. coli
	ASK1 protein is a key serine/threonine kinase in the MAP kinase pathway, coordinating cellular responses to environmental changes and affecting cell fate, differentiation, and survival. ASK1 is a key player in apoptosis and promotes mitochondria-dependent caspase activation. ASK1 Protein, Human (His) is the recombinant human-derived ASK1 protein, expressed by E. coli , with C-6*His labeled tag. The total length of ASK1 Protein, Human (His) is 298 a.a., .

HY-P701815

	MKNK2 Protein, Human (His) MKNK2; MAP Kinase-interacting serine/threonine-protein Kinase 2; MAP Kinase signal-integrating Kinase 2; MAPK signal-integrating Kinase 2; Mnk2	Human	E. coli
	MKNK2 is a serine/threonine protein kinase that centrally affects cellular processes by phosphorylating SFPQ/PSF, HNRNPA1, and EIF4E. MKNK2 sits at the intersection of environmental stress and cytokine signaling and regulates translation by enhancing the affinity of EIF4E for the mRNA cap, thereby affecting the translation machinery. MKNK2 Protein, Human (His) is the recombinant human-derived MKNK2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of MKNK2 Protein, Human (His) is 314 a.a., .

HY-P700593

	MAP3K1 Protein, Mouse (His) MEKK; MEKK1; SRXY6; MEKK 1; MAPKKK1; MAP/ERK Kinase Kinase 1; MAPK/ERK Kinase Kinase 1; MEK Kinase 1; mitogen-activated protein Kinase Kinase Kinase 1, E3 ubiquitin protein ligase; mitogen-activated protein Kinase Kinase Kinase 1	Mouse	E. coli
	MAP3K1 is a key component of the protein kinase signal transduction cascade and plays a crucial role in cell signaling pathways. Through its kinase activity, MAP3K1 coordinates the activation of the ERK and JNK kinase pathways by phosphorylating MAP2K1 and MAP2K4. MAP3K1 Protein, Mouse (His) is the recombinant mouse-derived MAP3K1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of MAP3K1 Protein, Mouse (His) is 278 a.a., with molecular weight of 34.8 kDa.

HY-P701813

	MKNK1 Protein, Human (Sf9, GST) MKNK1; MAP Kinase-interacting serine/threonine-protein Kinase 1; MAP Kinase signal-integrating Kinase 1; MAPK signal-integrating Kinase 1; Mnk1	Human	Sf9 insect cells
	MKNK1 (MAP Kinase Interacting Serine/Threonine Kinase 1) plays a central role in coordinating cellular responses to environmental stress and cytokines. It exerts regulatory control over translation processes by phosphorylating EIF4E, enhancing its affinity for mRNA cap structures with 7-methylguanosine. This highlights MKNK1's crucial involvement in finely tuning translation machinery in response to diverse cellular stimuli. MKNK1 Protein, Human (Sf9, GST) is the recombinant human-derived MKNK1 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of MKNK1 Protein, Human (Sf9, GST) is 424 a.a., .

HY-P702662

	MAPKAPK2 Protein, Human (323a.a) MAPKAPK2; mitogen-activated protein Kinase-activated protein Kinase 2; MAP Kinase-activated protein Kinase 2; MAPKAP Kinase 2; MAPK-activated protein Kinase 2; MK2; MK-2; MAPKAP-K2	Human	E. coli

HY-P701804

	MAPKAPK2 Protein, Human MAPKAPK2; MAP Kinase-activated protein Kinase 2; MAPK-activated protein Kinase 2; MAPKAP Kinase 2; MAPKAP-K2; MAPKAPK-2; MK-2; MK2	Human	E. coli
	The MAPKAPK2 protein is a stress-activated kinase involved in multiple cellular processes, including cytokine production, endocytosis, cytoskeletal reorganization, cell migration, cell cycle control, chromatin remodeling, DNA damage response, and transcriptional regulation. MAPKAPK2 Protein, Human is the recombinant human-derived MAPKAPK2 protein, expressed by E. coli , with tag free. and ΔH217-P237, S216G, , , mutation. The total length of MAPKAPK2 Protein, Human is 318 a.a., .

HY-P701730

	P38β Protein, Human (Sf9) MAPK11; Mitogen-activated protein Kinase 11; MAP Kinase 11; MAPK 11; Mitogen-activated protein Kinase p38 beta; MAP Kinase p38 beta; p38b; Stress-activated protein Kinase 2b; SAPK2b; p38-2	Human	Sf9 insect cells
	The P38β protein is an important serine/threonine kinase in the MAP kinase pathway that responds to extracellular stimuli, including proinflammatory cytokines and physical stress. As part of the p38 MAPK family, P38β directly activates transcription factors that phosphorylate many proteins, including RPS6KA5/MSK1 and RPS6KA4/MSK2. P38β Protein, Human (Sf9) is the recombinant human-derived P38β protein, expressed by Sf9 insect cells , with tag free. The total length of P38β Protein, Human (Sf9) is 363 a.a., .

HY-P701731

	P38β Protein, Human (Sf9, GST) MAPK11; Mitogen-activated protein Kinase 11; MAP Kinase 11; MAPK 11; Mitogen-activated protein Kinase p38 beta; MAP Kinase p38 beta; p38b; Stress-activated protein Kinase 2b; SAPK2b; p38-2	Human	Sf9 insect cells
	The P38β protein is an important serine/threonine kinase in the MAP kinase pathway that responds to extracellular stimuli, including proinflammatory cytokines and physical stress. As part of the p38 MAPK family, P38β directly activates transcription factors that phosphorylate many proteins, including RPS6KA5/MSK1 and RPS6KA4/MSK2. P38β Protein, Human (Sf9, GST) is the recombinant human-derived P38β protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of P38β Protein, Human (Sf9, GST) is 363 a.a., .

HY-P701798

	MAP2K7 Protein, Human (Sf9) MAP2K7; Dual specificity mitogen-activated protein Kinase Kinase 7; MAP Kinase Kinase 7; MAPKK 7; JNK-activating Kinase 2; MAPK/ERK Kinase 7; MEK 7; Stress-activated protein Kinase Kinase 4; SAPK Kinase 4; SAPKK-4; SAPKK4; c-Jun N-terminal Kinase Kinase 2; JNK Kinase 2; JNKK 2	Human	Sf9 insect cells
	MAP2K7 protein is a dual-specificity kinase involved in the MAP kinase signal transduction pathway. MAP2K7 Protein, Human (Sf9) is the recombinant human-derived MAP2K7 protein, expressed by Sf9 insect cells , with tag free. The total length of MAP2K7 Protein, Human (Sf9) is 418 a.a., .

HY-P700592

	MAP2K6 Protein, Human (Baculovirus, His) MAP2K6; mitogen-activated protein Kinase Kinase 6; MEK6; MKK6; MAPKK6; PRKMK6; SAPKK3; protein Kinase, mitogen-activated, Kinase 6 (MAP Kinase Kinase 6); EC 2.7.12.2; Dual specificity mitogen-activated protein Kinase Kinase 6; MAP Kinase Kinase 6; MAPK/ERK Kinase 6	Human	Sf9 insect cells
	The MKK6 protein is a dual-specificity kinase involved in the MAP kinase pathway. MAP2K6 Protein, Human (Baculovirus, His) is the recombinant human-derived MAP2K6 protein, expressed by Sf9 insect cells , with N-6*His labeled tag. The total length of MAP2K6 Protein, Human (Baculovirus, His) is 334 a.a., with molecular weight of 39.5 kDa.

HY-P701805

	MAPKAPK2 Protein, Human (His) MAPKAPK2; MAP Kinase-activated protein Kinase 2; MAPK-activated protein Kinase 2; MAPKAP Kinase 2; MAPKAP-K2; MAPKAPK-2; MK-2; MK2	Human	E. coli
	The MAPKAPK2 protein is a stress-activated kinase involved in multiple cellular processes, including cytokine production, endocytosis, cytoskeletal reorganization, cell migration, cell cycle control, chromatin remodeling, DNA damage response, and transcriptional regulation. MAPKAPK2 Protein, Human (His) is the recombinant human-derived MAPKAPK2 protein, expressed by E. coli , with N-6*His labeled tag and ΔH217-P237, S216G, , , mutation. The total length of MAPKAPK2 Protein, Human (His) is 318 a.a., .

HY-P701799

	MAP2K7 Protein, Human (Sf9, His, GST) MAP2K7; Dual specificity mitogen-activated protein Kinase Kinase 7; MAP Kinase Kinase 7; MAPKK 7; JNK-activating Kinase 2; MAPK/ERK Kinase 7; MEK 7; Stress-activated protein Kinase Kinase 4; SAPK Kinase 4; SAPKK-4; SAPKK4; c-Jun N-terminal Kinase Kinase 2; JNK Kinase 2; JNKK 2	Human	Sf9 insect cells
	MAP2K7 protein is a dual-specificity kinase involved in the MAP kinase signal transduction pathway. MAP2K7 Protein, Human (Sf9, His, GST) is the recombinant human-derived MAP2K7 protein, expressed by Sf9 insect cells , with N-8*His, N-GST labeled tag. The total length of MAP2K7 Protein, Human (Sf9, His, GST) is 418 a.a., .

HY-P700589

	MAP2K4 Protein, Human (P. pastoris, His-GST) MAP2K4; mitogen-activated protein Kinase Kinase 4; SERK1; dual specificity mitogen-activated protein Kinase Kinase 4; JNKK1; MEK4; MKK4; PRKMK4; MEK 4; MAPKK 4; SAPK Kinase 1; MAPK/ERK Kinase 4; SAPK/ERK Kinase 1; MAP Kinase Kinase 4; JNK-activated Kinase 1; JNK activating Kinase 1; JNK-activating Kinase 1; c-Jun N-terminal Kinase Kinase 1; stress-activated protein Kinase Kinase 1; JNKK; SEK1; MAPKK4; SAPKK1; SAPKK-1	Human	P. pastoris
	The MAP2K4 protein is a dual-specificity kinase involved in the MAP kinase pathway. MAP2K4 Protein, Human (P. pastoris, His-GST) is the recombinant human-derived MAP2K4 protein, expressed by P. pastoris , with N-6*His, N-GST labeled tag. The total length of MAP2K4 Protein, Human (P. pastoris, His-GST) is 398 a.a., with molecular weight of 71.5 kDa.

HY-P702663

	MAPKAPK3 Protein, Human (Active, sf9, GST) MAPKAPK3; mitogen-activated protein Kinase-activated protein Kinase 3; MAP Kinase-activated protein Kinase 3; 3pK; 3PK; MAPKAP3; MAPKAP Kinase 3; chromosome 3p Kinase; MAPK-activated protein Kinase 3; MK-3; MAPKAP-K3; MAPKAPK-3	Human	Sf9 insect cells

HY-P74168

	ERK2 Protein, Mouse (sf9) Mitogen-activated protein Kinase 1; MAPK 1; ERT1; ERK-2; p42-MAPK	Mouse	Sf9 insect cells
	ERK2 protein is an essential serine/threonine kinase in the MAP kinase pathway and cooperates with MAPK1/ERK2 in the complex MAPK/ERK cascade. Stimulated by KIT and KITLG/SCF, this pathway is central to cellular function, affecting growth, adhesion, survival, and differentiation through transcription, translation, and cytoskeletal regulation. ERK2 Protein, Mouse (sf9) is the recombinant mouse-derived ERK2 protein, expressed by Sf9 insect cells , with tag free. The total length of ERK2 Protein, Mouse (sf9) is 358 a.a., with molecular weight of ~37 kDa.

HY-P76532

	p38 gamma/MAPK12 Protein, Human (sf9) Mitogen-activated protein Kinase 12; Extracellular signal-regulated Kinase 6; ERK-6; SAPK3	Human	Sf9 insect cells
	p38 gamma/MAPK12 Protein, a vital serine/threonine kinase in the MAP kinase pathway, responds to extracellular stimuli like pro-inflammatory cytokines or stress. Leading to the activation of transcription factors such as ELK1 and ATF2, p38 MAPKs phosphorylate around 200 to 300 substrates each. MAPK12 contributes to myoblast differentiation, down-regulates cyclin D1 in response to hypoxia, and inhibits cell proliferation while promoting differentiation. It phosphorylates DLG1, impacting mRNA processing during osmotic shock, regulates UV-induced checkpoint signaling, influences glucose uptake, ensures normal kinetochore localization of PLK1, and positively regulates myogenic precursor cell expansion in muscle growth and regeneration. p38 gamma/MAPK12 Protein, Human (sf9) is the recombinant human-derived p38 gamma/MAPK12 protein, expressed by Sf9 insect cells , with tag free. and with residual Gly-Pro in N-terminal (not related to functional changes) mutation. The total length of p38 gamma/MAPK12 Protein, Human (sf9) is 367 a.a., with molecular weight of ~43 kDa.

HY-P75223

	ERK2 Protein, Human (sf9, His) Mitogen-activated protein Kinase 1; MAPK 1; ERT1; ERK-2; p42-MAPK	Human	Sf9 insect cells
	ERK2 Protein, a key component of the MAPK/ERK cascade, regulates diverse cellular processes such as transcription, translation, mitosis, apoptosis, endosomal dynamics, and Golgi apparatus fragmentation. Through phosphorylation, it modulates substrates including transcription factors, cytoskeletal elements, apoptosis regulators, translation regulators, protein kinases, and phosphatases. ERK2 Protein, Human (sf9, His) is the recombinant human-derived ERK2 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of ERK2 Protein, Human (sf9, His) is 360 a.a., with molecular weight of ~42 kDa.

HY-P73334

	p38 delta/MAPK13 Protein, Human (sf9, GST) Mitogen-activated protein Kinase 13; MAPK 13; PRKM13; SAPK4	Human	Sf9 insect cells
	The p38 delta/MAPK13 protein is an important serine/threonine kinase in the MAP kinase pathway. It coordinates cellular responses to stimuli such as cytokines or stress and directly activates the transcription factors ELK1 and ATF2. In this cascade, p38 MAPK (including MAPK13) each phosphorylates approximately 200 to 300 substrates. p38 delta/MAPK13 Protein, Human (sf9, GST) is the recombinant human-derived p38 delta/MAPK13 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of p38 delta/MAPK13 Protein, Human (sf9, GST) is 365 a.a., with molecular weight of ~63.9 kDa.

HY-P74167

	ERK2 Protein, Mouse (sf9, His-GST) Mitogen-activated protein Kinase 1; MAPK 1; ERT1; ERK-2; p42-MAPK	Mouse	Sf9 insect cells
	ERK2 protein is an essential serine/threonine kinase in the MAP kinase pathway and cooperates with MAPK1/ERK2 in the complex MAPK/ERK cascade. Stimulated by KIT and KITLG/SCF, this pathway is central to cellular function, affecting growth, adhesion, survival, and differentiation through transcription, translation, and cytoskeletal regulation. ERK2 Protein, Mouse (sf9, His-GST) is the recombinant mouse-derived ERK2 protein, expressed by Sf9 insect cells , with N-GST, N-His labeled tag. The total length of ERK2 Protein, Mouse (sf9, His-GST) is 358 a.a., with molecular weight of ~60 kDa.

HY-P76533

	p38 gamma/MAPK12 Protein, Human (sf9, His-GST) Mitogen-activated protein Kinase 12; Extracellular signal-regulated Kinase 6; ERK-6; SAPK3	Human	Sf9 insect cells
	The p38 gamma/MAPK12 protein is an important serine/threonine kinase in the MAP kinase pathway and can respond to extracellular stimuli such as pro-inflammatory cytokines or stress. p38 MAPK activates transcription factors such as ELK1 and ATF2, each of which phosphorylates approximately 200 to 300 substrates. p38 gamma/MAPK12 Protein, Human (sf9, His-GST) is the recombinant human-derived p38 gamma/MAPK12 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of p38 gamma/MAPK12 Protein, Human (sf9, His-GST) is 367 a.a., with molecular weight of ~65 kDa.

HY-P74794

	JNK2 Protein, Human (sf9, His) Mitogen-activated protein Kinase 9; MAPK 9; JNK-55; SAPK1a	Human	Sf9 insect cells
	JNK2 is a critical serine/threonine protein kinase that centrally regulates multiple cellular processes, including proliferation, apoptosis, and differentiation. JNK2 is activated by MAP2K4/MKK4 and MAP2K7/MKK7 in the SAP/JNK pathway and regulates AP-1 transcriptional activity by phosphorylating components such as JUN and ATF2. JNK2 Protein, Human (sf9, His) is the recombinant human-derived JNK2 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of JNK2 Protein, Human (sf9, His) is 424 a.a., with molecular weight of ~49.5 kDa.

HY-P73848

	JNK1 Protein, Human (sf9, GST) Mitogen-activated protein Kinase 8; MAPK 8; JNK-46; JNK1; PRKM8	Human	Sf9 insect cells
	JNK1 is a multifunctional serine/threonine protein kinase that complexly regulates multiple cellular processes, including cell proliferation, apoptosis, and differentiation. JNK1 is activated by MAP2K4/MKK4 and MAP2K7/MKK7, phosphorylates AP-1 components, and affects transcriptional activity. JNK1 Protein, Human (sf9, GST) is the recombinant human-derived JNK1 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of JNK1 Protein, Human (sf9, GST) is 427 a.a., with molecular weight of ~65 kDa.

HY-P73335

	p38 alpha/MAPK14 Protein, Human (Activated, sf9, His) Mitogen-activated protein Kinase 14; MAPK 14; CSBP; MXI2; SAPK2A	Human	Sf9 insect cells
	The p38 α/MAPK14 protein is an important serine/threonine kinase in the MAP kinase pathway. It can respond to stimuli such as cytokines or stress and directly activate transcription factors. In this cascade, p38 MAPK each phosphorylates approximately 200 to 300 substrates, including the downstream kinases RPS6KA5/MSK1 and RPS6KA4/MSK2, which are critical for immediate early gene induction. p38 alpha/MAPK14 Protein, Human (Activated, sf9, His) is the recombinant human-derived p38 alpha/MAPK14 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of p38 alpha/MAPK14 Protein, Human (Activated, sf9, His) is 360 a.a., with molecular weight of ~43.7 kDa.

HY-P701773

	RSK2 Protein, Human RPS6KA3; Ribosomal protein S6 Kinase alpha-3; S6K-alpha-3; 90 kDa ribosomal protein S6 Kinase 3; p90-RSK 3; p90RSK3; Insulin-stimulated protein Kinase 1; ISPK-1; MAP Kinase-activated protein Kinase 1b; MAPK-activated protein Kinase 1b; MAPKAP Kinase 1b; MAPKAPK-1b; Ribosomal S6 Kinase 2; RSK-2; pp90RSK2	Human	E. coli
	RSK2 is a kinase downstream of ERK signaling and plays a critical role in mediating mitosis and stress responses. It activates transcription factors (CREB1, ETV1, NR4A1), affecting proliferation, survival and differentiation. RSK2 Protein, Human is the recombinant human-derived RSK2 protein, expressed by E. coli , with tag free. The total length of RSK2 Protein, Human is 341 a.a., .

HY-P701774

	RSK2 Protein, Human (His) RPS6KA3; Ribosomal protein S6 Kinase alpha-3; S6K-alpha-3; 90 kDa ribosomal protein S6 Kinase 3; p90-RSK 3; p90RSK3; Insulin-stimulated protein Kinase 1; ISPK-1; MAP Kinase-activated protein Kinase 1b; MAPK-activated protein Kinase 1b; MAPKAP Kinase 1b; MAPKAPK-1b; Ribosomal S6 Kinase 2; RSK-2; pp90RSK2	Human	E. coli
	RSK2 is a kinase downstream of ERK signaling and plays a critical role in mediating mitosis and stress responses. It activates transcription factors (CREB1, ETV1, NR4A1), affecting proliferation, survival and differentiation. RSK2 Protein, Human (His) is the recombinant human-derived RSK2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of RSK2 Protein, Human (His) is 341 a.a., .

HY-P701771

	RSK1 Protein, Human (Sf9) RPS6KA1; Ribosomal protein S6 Kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 Kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP Kinase-activated protein Kinase 1a; MAPK-activated protein Kinase 1a; MAPKAP Kinase 1a; MAPKAPK-1a; Ribosomal S6 Kinase 1; RSK-1	Human	Sf9 insect cells
	RSK1 is a kinase downstream of ERK signaling and is critical for mitosis and stress-induced responses. It activates transcription factors (CREB1, ETV1, NR4A1), affecting proliferation, survival and differentiation. RSK1 Protein, Human (Sf9) is the recombinant human-derived RSK1 protein, expressed by Sf9 insect cells , with tag free. The total length of RSK1 Protein, Human (Sf9) is 321 a.a., .

HY-P701772

	RSK1 Protein, Human (Sf9, His) RPS6KA1; Ribosomal protein S6 Kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 Kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP Kinase-activated protein Kinase 1a; MAPK-activated protein Kinase 1a; MAPKAP Kinase 1a; MAPKAPK-1a; Ribosomal S6 Kinase 1; RSK-1	Human	Sf9 insect cells
	RSK1 is a kinase downstream of ERK signaling and is critical for mitosis and stress-induced responses. It activates transcription factors (CREB1, ETV1, NR4A1), affecting proliferation, survival and differentiation. RSK1 Protein, Human (Sf9, His) is the recombinant human-derived RSK1 protein, expressed by Sf9 insect cells , with N-8*His labeled tag. The total length of RSK1 Protein, Human (Sf9, His) is 321 a.a., .

HY-P702664

MAPKAPK5 Protein, Human (sf9, GST)

MAPKAPK5; MAPK activated protein Kinase 5; MK5; MK-5; NCFD; PRAK; MAPKAP-K5
Human Sf9 insect cells

HY-P70931

	MAPKSP1 Protein, Human (His) Ragulator Complex Protein LAMTOR3; Late Endosomal/Lysosomal Adaptor and MAPK and MTOR Activator 3; MEK-Binding Partner 1; Mp1; Mitogen-Activated Protein Kinase Kinase 1-Interacting Protein 1; Mitogen-Activated Protein Kinase Scaffold Protein 1; LAMTOR3; MAP2K1IP	Human	E. coli
	The MAPKSP1 protein, also known as porphobilinogen deaminase (HMBS), is crucial in the heme biosynthetic pathway and catalyzes the sequential polymerization of four porphobilinogen molecules to form hydroxymethyl bixane. The process begins with the assembly of the dipyrromethane cofactor of porphobilinogen or preuroporphyrinogen. MAPKSP1 Protein, Human (His) is the recombinant human-derived MAPKSP1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of MAPKSP1 Protein, Human (His) is 124 a.a., with molecular weight of ~15.0 kDa.

HY-P70921

	MBIP Protein, Human (His) MAP3K12-Binding Inhibitory Protein 1; MAPK Upstream Kinase-Binding Inhibitory Protein; MUK-Binding Inhibitory Protein; MBIP	Human	E. coli
	MBIP protein inhibits MAP3K12 activity and prevents activation of the JNK/SAPK pathway. It is an important component of the ATAC complex, a histone acetyltransferase complex targeting histones H3 and H4. MBIP Protein, Human (His) is the recombinant human-derived MBIP protein, expressed by E. coli , with N-6*His labeled tag. The total length of MBIP Protein, Human (His) is 344 a.a., with molecular weight of ~50.0 kDa.

Cat. No.	Product Name	Application	Reactivity

HY-P82888

MEKK3 Antibody (YA2633) MAP/ERK Kinase Kinase 3; MAP3K3; MAPK/ERK Kinase Kinase 3; MAPKKK3; MEK Kinase 3; MEKK 3; MEKK3; Mitogen activated protein Kinase Kinase Kinase 3	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat

HY-P81378

MAP4K4/NIK Antibody (YA1123) MAP4K4; HGK, KIAA0687, NIK; Mitogen-activated protein Kinase Kinase Kinase Kinase 4; HPK/GCK-like Kinase HGK; MAPK/ERK Kinase Kinase Kinase 4 (MEK Kinase Kinase 4; MEKKK 4); Nck-interacting Kinase	IHC-P	Human

HY-P83470

MEKK2 Antibody (YA3215)

MAP3K2; MAPKKK2; MEKK2; Mitogen-activated protein Kinase Kinase Kinase 2; MAPK/ERK Kinase Kinase 2; MEK Kinase 2; MEKK 2
WB, ICC/IF, IP Human, Mouse, Rat

HY-P83325

MAPKAP Kinase 3 Antibody (YA3070) MAPKAPK3; MAP Kinase-activated protein Kinase 3; MAPK-activated protein Kinase 3; MAPKAP Kinase 3; MAPKAP-K3; MAPKAPK-3; MK-3; Chromosome 3p Kinase; 3pK	WB, IP	Human

HY-P80549

ASK1 Antibody MAP3K5; ASK1; MAPKKK5; MEKK5; Mitogen-activated protein Kinase Kinase Kinase 5; Apoptosis signal-regulating Kinase 1; ASK-1; MAPK/ERK Kinase Kinase 5; MEK Kinase 5; MEKK 5	WB, IHC-P, ICC/IF, FC	Human, Mouse
ASK1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 155 kDa, targeting to ASK1. It can be used for WB,IHC-P,ICC/IF,FC assays with tag free, in the background of Human, Mouse.

HY-P83469

MEK3 Antibody (YA3214) AW212142; dual specificity mitogen activated protein Kinase Kinase 3; Dual specificity mitogen activated protein Kinase Kinase 6; Dual specificity mitogen-activated protein Kinase Kinase 3; MAP Kinase Kinase 3; MAP Kinase Kinase 6; map2k3; MAP2K6; MAPK ERK Kinase 3; MAPK/ERK Kinase 3; MAPK/ERK Kinase 6; MAPKK 3; MAPKK 6; MAPKK3; MAPKK6; MEK 3; MEK 6; MEK3; Mitogen activated protein Kinase Kinase 3; Mitogen activated protein Kinase Kinase 6; MKK 3; MKK3; MKK6; mMKK3b; MP2K3_HUMAN; PRKMK 3; PRKMK3; PRKMK6; Protein Kinase; mitogen activated; Kinase 6 (MAP Kinase Kinase 6); protein Kinase; mitogen-activated; Kinase 3; SAPK Kinase 2; SAPKK 2; SAPKK 3; SAPKK-2; SAPKK2; SAPKK3; Stress activated protein Kinase Kinase 2; Stress activated protein Kinase Kinase 3; Stress-activated protein Kinase Kinase 2.	WB, ICC/IF, IP	Human, Mouse, Rat

HY-P80792

Phospho-ASK1 (Ser966) Antibody MAP3K5; ASK1; MAPKKK5; MEKK5; Mitogen-activated protein Kinase Kinase Kinase 5; Apoptosis signal-regulating Kinase 1; ASK-1; MAPK/ERK Kinase Kinase 5; MEK Kinase 5; MEKK 5	WB, IHC-P	Human, Mouse, Rat
Phospho-ASK1 (Ser966) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 155 kDa, targeting to Phospho-ASK1 (Ser966). It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse, Rat.

HY-P81156

phospho-ERK1 + 2 (Thr183/Tyr185) Antibody ERK1 + ERK2 (phospho Thr183/Tyr185); phospho-ERK1/MAPK-1/2(Thr183/Tyr185); ERK 1; ERK 2; ERK-2; ERK1; ERK2; ERT1; ERT2; Extracellular signal regulated Kinase 1; Extracellular signal regulated Kinase 1; Extracellular signal regulated Kinase 2; Extracellular signal regulated Kinase 2; Extracellular signal-regulated Kinase 2; HS44KDAP; HUMKER1A; Insulin stimulated MAP2 Kinase; MAP Kinase 1; MAP Kinase 2; MAP Kinase isoform p42; MAP Kinase isoform p44; MAPK 1; MAPK 2; MAPK1; MAPK2; MGC20180; Microtubule associated protein 2 Kinase; Mitogen activated protein Kinase 1; Mitogen activated protein Kinase 1; Mitogen activated protein Kinase 2; Mitogen-activated protein Kinase 1; Mitogen-activated protein Kinase 2; MK01_MOUSE; p38; p40; p41; p41MAPK; p42 MAPK; p42-MAPK; p42MAPK; p42MAPK; p44 ERK1; p44 MAPK; p44ERK1; p44ERK1; p44MAPK; p44MAPK; PRKM 1; PRKM 1; PRKM 2; PRKM 2; PRKM1; PRKM2; Protein Kinase mitogen activated 1; Protein Kinase mitogen activated 1; Protein Kinase mitogen activated 2; Protein Kinase mitogen activated 2; Protein tyrosine kinas.	WB; ELISA; IHC-P; IHC-F; ICC; IF	Human, Mouse(predicted: Rat, Chicken, Dog, Cow, Horse, Rabbit, Guinea Pig)
phospho-ERK1 + 2 (Thr183/Tyr185) Antibody is an unconjugated, approximately 42/44 kDa, rabbit-derived, anti-phospho-ERK1 + 2 (Thr183/Tyr185) polyclonal antibody. phospho-ERK1 + 2 (Thr183/Tyr185) Antibody can be used for: WB, ELISA, IHC-P, IHC-F, ICC, IF expriments in human, mouse, and predicted: rat, chicken, dog, cow, horse, rabbit, guinea pig background without labeling.

HY-P83405

JNK3 Antibody (YA3150) Mitogen-activated protein Kinase 10; MAP Kinase 10; MAPK 10; MAP Kinase p49 3F12; Stress-activated protein Kinase 1b; SAPK1b; MAPK10; JNK3; JNK3A; PRKM10; SAPK1B	WB, ICC/IF, FC	Human, Mouse, Rat

HY-P80728

JNK Antibody AI849689; c Jun N terminal Kinase 1; C-JUN Kinase 1; c-Jun N-terminal Kinase 1; EC 2.7.11.24; JAK 1A; JAK1A; JNK 1; JNK 46; JNK; JNK-46; JNK1A2; JNK21B1/2; MAP Kinase 8; MAPK 8; MAPK8; Mitogen activated protein Kinase 8; Mitogen-activated protein Kinase 8	WB, IP	Human, Mouse, Rat, Hamster
JNK Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 48 kDa, targeting to JNK. It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat, Hamster.

HY-P82902

MEK7 Antibody (YA2647) MAP2K7; JNKK2; MEK7; MKK7; PRKMK7; SKK4; Dual specificity mitogen-activated protein Kinase Kinase 7; MAP Kinase Kinase 7; MAPKK 7; JNK-activating Kinase 2; MAPK/ERK Kinase 7; MEK 7; Stress-activated protein Kinase Kinase 4; SAPK Kinase 4; S	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat

HY-P83314

MEK2 Antibody (YA3059) MAP2K2; MEK2; MKK2; PRKMK2; Dual specificity mitogen-activated protein Kinase Kinase 2; MAP Kinase Kinase 2; MAPKK 2; ERK activator Kinase 2; MAPK/ERK Kinase 2; MEK 2	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse

HY-P81343

MAP2K6 Antibody (YA1088) MAP2K6; MEK6; MKK6; PRKMK6; SKK3; Dual specificity mitogen-activated protein Kinase Kinase 6; MAP Kinase Kinase 6; MAPKK 6; MAPK/ERK Kinase 6; MEK 6; Stress-activated protein Kinase Kinase 3; SAPK Kinase 3; SAPKK-3; SAPKK3	WB, IP	Human, Rat

HY-P80832

Phospho-MEK1 (Ser298) Antibody MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein Kinase Kinase 1; MAP Kinase Kinase 1; MAPKK 1; MKK1; ERK activator Kinase 1; MAPK/ERK Kinase 1; MEK 1	WB, ICC/IF	Human, Mouse, Rat
Phospho-MEK1 (Ser298) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 43 kDa, targeting to Phospho-MEK1 (Ser298). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P80833

Phospho-MEK1 (Thr292) Antibody MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein Kinase Kinase 1; MAP Kinase Kinase 1; MAPKK 1; MKK1; ERK activator Kinase 1; MAPK/ERK Kinase 1; MEK 1	WB	Mouse, Rat
Phospho-MEK1 (Thr292) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 43 kDa, targeting to Phospho-MEK1 (Thr292). It can be used for WB assays with tag free, in the background of Mouse, Rat.

HY-P80729

JNK1 Antibody (YA720) AI849689; c Jun N terminal Kinase 1; C-JUN Kinase 1; c-Jun N-terminal Kinase 1; EC 2.7.11.24; JAK 1A; JAK1A; JNK 1; JNK 46; JNK; JNK-46; JNK1A2; JNK21B1/2; MAP Kinase 8; MAPK 8; MAPK8; Mitogen activated protein Kinase 8; Mitogen-activated protein Kinase 8	WB, ICC/IF	Human, Mouse, Rat
JNK1 (1A4) Antibody is a non-conjugated and Mouse origined monoclonal antibody about 48 kDa, targeting to JNK1 (1A4). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P83395

MEK5 Antibody (YA3140)

MAP2K5; MEK5; MKK5; PRKMK5; Dual specificity mitogen-activated protein Kinase Kinase 5; MAP Kinase Kinase 5; MAPKK 5; MAPK/ERK Kinase 5; MEK 5
WB, ICC/IF Human

HY-P80831

Phospho-JNK1 (Thr183/Tyr185) Antibody AI849689; c Jun N terminal Kinase 1; C-JUN Kinase 1; c-Jun N-terminal Kinase 1; EC 2.7.11.24; JAK 1A; JAK1A; JNK 1; JNK 46; JNK; JNK-46; JNK1A2; JNK21B1/2; MAP Kinase 8; MAPK 8; MAPK8; Mitogen activated protein Kinase 8; Mitogen-activated protein Kinase 8	WB, IP	Human, Rat
Phospho-JNK1 (Thr183/Tyr185) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 48 kDa, targeting to Phospho-JNK1 (Thr183/Tyr185). It can be used for WB,IP assays with tag free, in the background of Human, Rat.

HY-P80834

Phospho-MEK4 (Ser80) Antibody MAP2K4; JNKK1; MEK4; MKK4; PRKMK4; SEK1; SERK1; SKK1; Dual specificity mitogen-activated protein Kinase Kinase 4; MAP Kinase Kinase 4; MAPKK 4; JNK-activating Kinase 1; MAPK/ERK Kinase 4; MEK 4; SAPK/ERK Kinase 1; SEK1; Stress-activated pro	WB, IP	Human
Phospho-MEK4 (Ser80) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 44 kDa, targeting to Phospho-MEK4 (Ser80). It can be used for WB,IP assays with tag free, in the background of Human.

HY-P80777

p38 Antibody MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; Mitogen-activated protein Kinase 14; MAP Kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP Kinase MXI2; MAX-interacting protein	WB, IP	Human
p38 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 41 kDa, targeting to p38. It can be used for WB,IP assays with tag free, in the background of Human.

HY-P80776

p38 Antibody (YA696) MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; Mitogen-activated protein Kinase 14; MAP Kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP Kinase MXI2; MAX-interacting protein	WB	Human, Mouse, Rat, Monkey
p38 Antibody (YA696) is a non-conjugated and Mouse origined monoclonal antibody about 41 kDa, targeting to p38 (5A1). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat, Monkey.

HY-P83578

MEK3/MEK6 Antibody (YA3323)

MEK6; MKK6; MAPKK6; PRKMK6; SAPKK3; MAP2K6; MEK3; MAP Kinase Kinase 3; MAPKK3; MAPK/ERK Kinase 3
WB, ICC/IF, IP Human, Mouse

HY-P80842

Phospho-p38 (Thr180/Tyr182) Antibody MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; Mitogen-activated protein Kinase 14; MAP Kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP Kinase MXI2; MAX-interacting protein	WB	Human, Mouse, Rat
Phospho-p38 (Thr180/Tyr182) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 41 kDa, targeting to Phospho-p38 (Thr180/Tyr182). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P80850

Phospho-RSK2 (Ser227) Antibody RPS6KA3; ISPK1; MAPKAPK1B; RSK2; Ribosomal protein S6 Kinase alpha-3; S6K-alpha-3; 90 kDa ribosomal protein S6 Kinase 3; p90-RSK 3; p90RSK3; Insulin-stimulated protein Kinase 1; ISPK-1; MAP Kinase-activated protein Kinase 1b; MAPK-activated	WB, IP	Human, Mouse, Rat
Phospho-RSK2 (Ser227) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 84 kDa, targeting to Phospho-RSK2 (Ser227). It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat.

HY-P80887

RSK3 Antibody RPS6KA2; MAPKAPK1C; RSK3; Ribosomal protein S6 Kinase alpha-2; S6K-alpha-2; 90 kDa ribosomal protein S6 Kinase 2; p90-RSK 2; p90RSK2; MAP Kinase-activated protein Kinase 1c; MAPK-activated protein Kinase 1c; MAPKAP Kinase 1c; MAPKAPK-1c; Ri	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Hamster
RSK3 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 83 kDa, targeting to RSK3. It can be used for WB,IHC-F,IHC-P,ICC/IF,IP assays with tag free, in the background of Human, Hamster.

HY-P80848

Phospho-RSK1 p90 (Ser380) Antibody RPS6KA1; MAPKAPK1A; RSK1; Ribosomal protein S6 Kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 Kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP Kinase-activated protein Kinase 1a; MAPK-activated protein Kinase 1a; MAPKAP Kinase 1a; MAPKAP	WB, ICC/IF, IP	Human, Rat, Mouse
Phospho-RSK1 p90 (Ser380) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 83 kDa, targeting to Phospho-RSK1 p90 (Ser380). It can be used for WB, ICC/IF, IP assays with tag free, in the background of Human, Mouse and Rat.

HY-P80886

RSK1 p90 Antibody (YA676) RPS6KA1; MAPKAPK1A; RSK1; Ribosomal protein S6 Kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 Kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP Kinase-activated protein Kinase 1a; MAPK-activated protein Kinase 1a; MAPKAP Kinase 1a; MAPKAP	WB, IP	Human, Mouse, Monkey
RSK1 p90 Antibody (YA676) is a non-conjugated and Mouse origined monoclonal antibody about 83 kDa, targeting to RSK1 p90 (6B9). It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Monkey.

HY-P80849

Phospho-RSK1 p90 (Thr359/Ser363) Antibody RPS6KA1; MAPKAPK1A; RSK1; Ribosomal protein S6 Kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 Kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP Kinase-activated protein Kinase 1a; MAPK-activated protein Kinase 1a; MAPKAP Kinase 1a; MAPKAP	WB, IP	Human, Mouse, Rat
Phospho-RSK1 p90 (Thr359/Ser363) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 83 kDa, targeting to Phospho-RSK1 p90 (Thr359/Ser363). It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat.

HY-P80776A

Phospho-p38 (Thr180+Tyr182) Antibody p38 (phospho T180 + Y182); p-p38 (phospho T180 + Y182); p38 (phospho T180/Y182); CSAID Binding Protein 1; CSAID binding protein; CSAID-binding protein; Csaids binding protein; CSBP 1; CSBP 2; CSBP; CSBP1; CSBP2; CSPB 1; CSPB1; Cytokine suppressive anti inflammatory drug binding protein; Cytokine suppressive anti-inflammatory drug-binding protein; EXIP; MAP Kinase 14; MAP Kinase MXI2; MAP Kinase p38 alpha; MAPK 14; MAPK14; MAX interacting protein 2; MAX-interacting protein 2; Mitogen Activated Protein Kinase 14; Mitogen activated protein Kinase p38 alpha; Mitogen-activated protein Kinase 14; Mitogen-activated protein Kinase p38 alpha; MK14_HUMAN; Mxi 2; Mxi2; p38 ALPHA; p38; p38 MAP Kinase; p38 MAPK; p38 mitogen activated protein Kinase; p38ALPHA; p38alpha Exip; PRKM14; PRKM15; RK; SAPK 2A; SAPK2A; Stress Activated Protein Kinase 2A.	WB, IHC-P, Flow-Cyt, ICC, ELISA	Human, Mouse (predicted: Rat, Rabbit, Pig, Chicken, Dog, Horse)

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